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Background. Overproduction of type I collagen in fibroblasts of systemic sclerosis (SSc) is the hallmark of fibrosis. Establishment and characterization of the phenotype of SSc fibroblasts has been hindered by the heterogeneity between fibroblasts and the lack of adequate cloning methods.
Aim. To establish and investigate the characteristics of the SSc high collagen‐producing fibroblast phenotype...
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