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A simple, efficient, and environmentally friendly approach has been developed for the synthesis of peptides in aqueous medium. In this work, peptides are easily synthesized in water extract of banana (WEB)/ethylene glycol and without using external base under mild condition.
Urea assisting easy and greener synthesis of 1,4-disubstituted 1,2,3-triazoles has been achieved using copper(I)-catalyzed azide–alkyne cycloaddition (CuAAC) reaction in water. The click reaction affords notable features, such as high efficiency and regioselectivity, mild reaction conditions, easy operation, and excellent yields with a broad spectrum of substrates.
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