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ObjectivesCardiac apoptosis was found in ovariectomized rats without ischemia. Limited information regarding the protective effects of 17β‐estradiol (E2) on cardiac Fas‐dependent and mitochondria‐dependent apoptotic pathways after post‐menopause or bilateral oophorectomy in women was available.
MethodsForty‐eight female Wistar rats at 6‐7 months of age were divided into sham‐operated group (Sham,...
Very limited information has been published regarding cardiac apoptosis in menopausal women or in those after bilateral oophorectomy. The purpose of this study was to evaluate whether cardiac Fas-dependent (type I) and mitochondria-dependent (type II) apoptotic pathways are activated in ovariectomized rats.Thirty-two female Wistar rats at 6–7 months of age were randomly divided into sham-operated...
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