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Selected strains of Pseudomonas bacteria can degrade tropane alkaloids to obtain both nitrogen and carbon for growth. In order to probe the mechanisms of the catabolic enzymes involved, the metabolic process responsible for the opening of the 8-azabicyclo[3.2.1]octan-3-ol ring of nortropane alkaloids has been explored. It is found that the bacteria contain considerable flexibility in their enzyme...
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