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The synthesis, pharmacological analysis and molecular modeling of the readily available racemic tacrine analogs 21–30, bearing the 7-aryl-9,10,11,12-tetrahydro-7H-benzo[7,8]chromeno[2,3-b]quinolin-8-amine heterocyclic ring system (II), prepared by Friedländer reaction of 2-amino-4-aryl-4H-benzo[h]chromene-3-carbonitriles (11–20) with cyclohexanone, are described in this paper. Molecules 21–30 are...
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