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Somatostatin (SRIF) SS-1 binding sites were initially defined in radioligand binding studies performed in rat brain cerebral cortex membranes using [ 125 I]204-090 (a radiolabelled Tyr 3 analogue of SMS 201-995, octreotide). SRIF-1 recognition sites were defined in binding studies performed with [ 125 I]MK 678 (seglitide). Both SS-1 and SRIF-1 sites were...
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