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Das antimikrobielle Protein Snakin‐1, …. … das aus Kartoffeln isoliert wurde, liegt in einer einzigartigen gefalteten dreidimensionalen Struktur mit sechs fixierenden Disulfidbrücken vor. In ihrer Zuschrift auf S. 8062 ff. nutzten M. A. Brimble, C. J. Squire et al. eine strahlenschädeninduzierte Phasierung (RIP), um die racemische Kristallstruktur des Proteins zu lösen. Dabei kam ihnen der spezifische...
Proteins from the GASA/snakin superfamily are common in plant proteomes and have diverse functions, including hormonal crosstalk, development, and defense. One 63‐residue member of this family, snakin‐1, an antimicrobial protein from potatoes, has previously been chemically synthesized in a fully active form. Herein the 1.5 Å structure of snakin‐1, determined by a novel combination of racemic protein...
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