Search results for: Sung-Wook Choi

Items from 1 to 20 out of 117 results

article

Octyl gallate has potent anti‐inflammasome activity by directly binding to NLRP3 LRR domain

Hana Park, Ryeojin Ko, Jeongin Seo, Guk Young Ahn, more

Journal of Cellular Physiology > 239 > 4 > n/a - n/a

The NOD‐, LRR‐, and Pyrin domain‐containing protein 3 (NLRP3) inflammasome plays key roles in regulating inflammation. Numerous studies show that the abnormal activation of NLRP3 associates with the initiation and progression of various diseases. Hence, the NLRP3 inflammasome may be a promising therapeutic target for these diseases. Octyl gallate (OG) is a small molecule with antioxidant, antimicrobial,...

article

In Situ Spontaneous Fabrication of Tough and Stretchable Polyurethane‐Polyethyleneimine Hydrogels Selectively Triggered by CO₂

Minju Song, Kangho Choi, Inseong Choi, Soo‐Kyung Han, more

Macromolecular Rapid Communications > 43 > 21 > n/a - n/a

CO₂‐triggered in situ hydrogels is developed from waterborne poly(ε‐caprolactone)‐based polyurethane (PU) dispersion and aqueous polyethyleneimine (PEI) solution without any other chemicals and apparatus (e.g., UV light). In the approach, nontoxic CO₂ in air is used as a selective trigger for the hydrogel formation. CO₂ adsorption onto PEI results in the formation of ammonium cations in PEI and the...

article

Fabrication of Biodegradable Polyurethane Foam Scaffolds with Customized Shapes and Controlled Mechanical Properties by Gas Foaming Technique

Soo Kyung Han, Minju Song, Kangho Choi, Sung‐Wook Choi

Macromolecular Materials and Engineering > 306 > 7 > n/a - n/a

Poly(ε‐caprolactone) (PCL)‐based polyurethane (PU) foam scaffolds with different mechanical properties are fabricated using a gas foaming technique to use as porous substitutes for ear or bone with cartilage. PCL diol or triol is used as a polyol in PU foam for biocompatibility and biodegradation, with an aqueous gelatin solution as a blowing agent. The highly porous inner and outer structures of...

article

Fabrication of nanodiamonds modified with hyaluronic acid and chlorin e6 for selective photothermal and photodynamic tumor therapy

Tae Hoon Yun, Guk‐Young Ahn, Inseong Choi, Yeon‐Ju Bae, more

Polymers for Advanced Technologies > 31 > 12 > 2990 - 2998

Nanodiamond (ND)‐based nanoparticles with hyaluronic acid (HA) and chlorin e6 (Ce6) were fabricated for potential photodynamic and photothermal tumor therapy. The ND nanoparticles conjugated with HA and Ce6 (Ce6‐ND@HA) had a suitable size range about 130 nm and high zeta‐potential about −35 mV. The conjugation was confirmed by UV‐vis spectroscopy and the conjugation efficiency of Ce6 in these ND nanoparticles...

article

Magnetic solid‐phase extraction based on magnetic carbon particles from coffee grounds for determining phthalic acid esters in plastic bottled water

Nho‐Eul Song, Min‐Cheol Lim, Sung‐Wook Choi, Dae‐Ok Kim, more

Journal of Food Science > 85 > 4 > 1098 - 1104

Abstract Newly developed magnetic carbon particles prepared from coffee grounds were used as the sorbent for the magnetic solid‐phase extraction of eight phthalic acid esters (PAEs) from plastic bottled water prior to their analysis by GC‐MS. The method, which uses coffee‐ground particles coated with iron oxide, was validated, and exhibited linearities for the eight PAEs, with coefficients of determination...

article

Curcumin‐loaded biodegradable polyurethane scaffolds modified with gelatin using 3D printing technology for cartilage tissue engineering

Min Jeong Lee, Sung Eun Kim, Juri Park, Guk Young Ahn, more

Polymers for Advanced Technologies > 30 > 12 > 3083 - 3090

We described the curcumin‐loaded biodegradable polyurethane (PU) scaffolds modified with gelatin based on three‐dimensional (3D) printing technology for potential application of cartilage regeneration. The printing solution of poly(ε‐caprolactone) (PCL) triol (polyol) and hexamethylene diisocyanate (HMDI) in 2,2,2‐trifluoroethanol was printed through a nozzle in dimethyl sulfoxide phase with or without...

article

Synthesis and Characterizations of Biodegradable Polyurethane Microspheres with Dexamethasone for Drug Delivery

Juri Park, Min Jeong Lee, Guk Young Ahn, Tae Hoon Yun, more

Macromolecular Research > 2019 > 27 > 9 > 839-842

This manuscript reports on the synthesis of biodegradable polyurethanes (PU) using poly(ε-caprolactone) diol and fabrication of microspheres containing dexamethasone (DEX). Biodegradable PUs with different isocyanate ratios were successfully synthesized using PCL diol as a polyol. The PU with a high isocyanate ratio exhibited a low average molecular weight, high melting point, high Young’s modulus,...

article

Dielectric traces of food materials in the terahertz region

Hee Jun Shin, Seung Jae Oh, Min-Cheol Lim, Sung-Wook Choi, more

Infrared Physics & Technology > 2018 > 92 > C > 128-133

We investigated the feasibility of identifying food products using the complex dielectric constant of food materials, and insects as a foreign substance, in the terahertz (THz) frequency range from 0.3 to 1.2 THz. Although the food and insect materials have unique dielectric properties, several materials could not be distinguished by the dielectric constant. To discriminate all food materials completely,...

article

One‐Step Fabrication of Uniform Biodegradable Microbeads with Unimodal and Bimodal Porous Structures Using Spontaneous Microphase Separation

Seung Woon Baek, Seung‐Kwan Moon, Rae Hyung Kang, Youngchang Ah, more

Macromolecular Materials and Engineering > 303 > 7 > n/a - n/a

Uniform poly(l‐lactic acid) (PLLA) microbeads with unimodal or bimodal porous structures are fabricated using a simple fluidic device based on a single oil‐in‐water emulsion method, where an alkane (octane, undecane, tridecane, and pentadecane) serves as the porogen. During the solvent evaporation, the alkanes spontaneously undergo a microphase separation, resulting in a highly porous structure. The...

article

Fabrication and optimization of Nanodiamonds-composited poly(ε-caprolactone) fibrous matrices for potential regeneration of hard tissues

Guk Young Ahn, Tae-Kyung Ryu, Yu Ri Choi, Ju Ri Park, more

Biomaterials Research > 2018 > 22 > 1 > 1-8

Background Electrospun fibrous matrices are of great importance for tissue engineering and drug delivery device. However, relatively low mechanical strength of the fibrous matrix is one of the major disadvantages. NDs with a positive charge were selected to enhance the mechanical property of a composited fibrous matrix by inducing the intermolecular interaction between NDs and polymer chain. We prepared...

article

Qualitative identification of food materials by complex refractive index mapping in the terahertz range

Hee Jun Shin, Sung-Wook Choi, Gyeongsik Ok

Food Chemistry > 2018 > 245 > C > 282-288

We investigated the feasibility of qualitative food analysis using complex refractive index mapping of food materials in the terahertz (THz) frequency range. We studied optical properties such as the refractive index and absorption coefficient of food materials, including insects as foreign substances, from 0.2 to 1.3 THz. Although some food materials had a complex composition, their refractive indices...

article

Electrosprayed Folic Acid-Conjugated Ursolic Acid Nanoparticles for Tumor Therapy

Guk Young Ahn, Dong-Hyun Paik, Ki-Young Jeong, Seung-Woon Baek, more

Macromolecular Research > 2018 > 26 > 7 > 573-576

We describe a simple method for the fabrication of folic acid-conjugated ursolic acid (FA-UA) nanoparticles using electrospraying. The FA-UA nanoparticles had an average size of 90.6 nm and exhibited greater cellular uptake compared with pristine UA and electrosprayed UA nanoparticles. We also evaluated the cytotoxicity of pristine UA, electrosprayed UA nanoparticles, and FA-UA nanoparticles over...

article

A heptameric peptide isolated from the marine microalga Pavlova lutheri suppresses PMA-induced secretion of matrix metalloproteinase-9 through the inactivation of the JNK, p38, and NF-κB pathways in human fibrosarcoma cells

Seok-Chun Ko, Seong-Yeong Heo, Sung-Wook Choi, Zhong-Ji Qian, more

Journal of Applied Phycology > 2018 > 30 > 4 > 2367-2378

In this study we isolate a heptameric peptide from the marine microalga Pavlova lutheri and examine its inhibitory effect and mechanism of action on the matrix metalloproteinase-9 (MMP-9) protein in human fibrosarcoma HT1080 cells. Through consecutive rounds of purification we isolated a potent MMP-9 inhibitory peptide composed of seven amino acids: Leu-Leu-Ala-Pro-Pro-Glu-Arg (796.4 Da). We show...

article

140-GHz subwavelength transmission imaging for foreign body inspection in food products

Gyeongsik Ok, Kisang Park, Min-Cheol Lim, Hyun-Joo Jang, more

Journal of Food Engineering > 2018 > 221 > C > 124-131

Non-diffractive beam scanning in the millimeter and terahertz wave ranges can provide extended depths of focus and high spatial resolutions for foreign body imaging inspection in food products. Here, an axicon lens was utilized to focus a 140-GHz Bessel–Gauss beam carrying a finite energy and realizing such a beam. An axicon lens array was employed to acquire transmission images using this beam. Even...

article

Photodynamic and photothermal tumor therapy using phase-change material nanoparticles containing chlorin e6 and nanodiamonds

Tae-Kyung Ryu, Seung-Woon Baek, Rae-Hyung Kang, Ki-Young Jeong, more

Journal of Controlled Release > 2018 > 270 > C > 237-245

This paper describes the fabrication and evaluation of phase-change material (PCM) nanoparticles containing chlorin e6 (Ce6) and nanodiamonds (NDs) for photodynamic and photothermal approaches for tumor therapy, respectively. The temperature of the PCM nanoparticles containing NDs (ND/PCM, 0.5mg/mL in water) is increased to 45°C during laser exposure for 5min. The singlet oxygen generation intensity...

article

A study on amphiphilic fluorinated block copolymer in graphite exfoliation using supercritical CO2 for stable graphene dispersion

Young Hyun Kim, Hyang Moo Lee, Sung Wook Choi, In Woo Cheong

Journal of Colloid and Interface Science > 2018 > 510 > C > 162-171

In this study, poly(2,2,2-trifluoroethyl methacrylate)-block-poly(4-vinylpyridine) (PTFEMA-b-PVP) was synthesized by stepwise reversible addition-fragmentation chain transfer (RAFT) polymerization for the preparation of graphene by the exfoliation of graphite nanoplatelets (GPs) in supercritical CO₂ (SCCO₂). Two different block copolymers (low and high molecular weights) were prepared with the same...

article

Thermally controllable filter at terahertz region

Hee Jun Shin, Min-Cheol Lim, Sae-Hyung Kim, Kisang Park, more

Infrared Physics & Technology > 2018 > 88 > C > 139-143

We experimentally investigated terahertz (THz) filters fabricated using dodecanoic acid (DDA) particles and polyethylene (PE) by performing THz time-domain spectroscopy. Since the refractive indices of DDA and PE are the same in the THz range, no optical scattering occurred when they were mixed. However, heating caused air voids to replace the DDA particles, and the DDA melted into the spaces between...

article

Free-standing guided-mode resonance humidity sensor in terahertz

Hee Jun Shin, Sae-Hyung Kim, Kisang Park, Min-Cheol Lim, more

Sensors and Actuators A: Physical > 2017 > 268 > C > 27-31

We theoretically and experimentally investigate a polymer-based guided-mode resonance (GMR) structure and its application for relative humidity (RH) sensing in the terahertz region. We obtained RH-dependent resonance frequency shifts and transmittance changes of the free-standing polymer GMR sensors with PVA material coating at 20°C. We numerically simulated the GMR structure in the same frequency...

article

Genetic diversity, antimicrobial resistance, toxin gene profiles, and toxin production ability of Bacillus cereus isolates from doenjang, a Korean fermented soybean paste

Nari Lee, Myo‐Deok Kim, Hyun‐Joo Chang, Sung‐Wook Choi, more

Journal of Food Safety > 37 > 4 > n/a - n/a

The objectives of this study were to determine the toxin gene profile, toxin production, and antibiotic resistance of Bacillus cereus isolates from doenjang, a Korean fermented soybean paste. Repetitive element sequence polymorphism‐PCR (rep‐PCR) was also used to assess the genetic diversity between these isolates. Thirty‐five B. cereus strains were isolated from 67 commercial doenjang samples, and...

article

Facile preparation of gold-coated polydimethylsiloxane particles by in situ reduction without pre-synthesized seed

Min-Cheol Lim, Kisang Park, Sae-Hyung Kim, Gyeongsik Ok, more

Colloids and Surfaces A: Physicochemical and Engineering Aspects > 2017 > 529 > C > 916-921

Herein, we develop a facile strategy for the preparation of polydimethylsiloxane (PDMS) microparticles decorated with gold nanoparticles (AuNPs) by the reduction of gold chloride on the surface of PDMS microparticles using sodium citrate. To prepare the AuNP-seeded particles, AuNP-seeded PDMS microparticles were simply produced in situ by the reduction of a PDMS curing agent without the use of any...

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INFONA - science communication portal

Search results for: Sung-Wook Choi

Octyl gallate has potent anti‐inflammasome activity by directly binding to NLRP3 LRR domain

In Situ Spontaneous Fabrication of Tough and Stretchable Polyurethane‐Polyethyleneimine Hydrogels Selectively Triggered by CO₂

Fabrication of Biodegradable Polyurethane Foam Scaffolds with Customized Shapes and Controlled Mechanical Properties by Gas Foaming Technique

Fabrication of nanodiamonds modified with hyaluronic acid and chlorin e6 for selective photothermal and photodynamic tumor therapy

Magnetic solid‐phase extraction based on magnetic carbon particles from coffee grounds for determining phthalic acid esters in plastic bottled water

Curcumin‐loaded biodegradable polyurethane scaffolds modified with gelatin using 3D printing technology for cartilage tissue engineering

Synthesis and Characterizations of Biodegradable Polyurethane Microspheres with Dexamethasone for Drug Delivery

Dielectric traces of food materials in the terahertz region

One‐Step Fabrication of Uniform Biodegradable Microbeads with Unimodal and Bimodal Porous Structures Using Spontaneous Microphase Separation

Fabrication and optimization of Nanodiamonds-composited poly(ε-caprolactone) fibrous matrices for potential regeneration of hard tissues

Qualitative identification of food materials by complex refractive index mapping in the terahertz range

Electrosprayed Folic Acid-Conjugated Ursolic Acid Nanoparticles for Tumor Therapy

A heptameric peptide isolated from the marine microalga Pavlova lutheri suppresses PMA-induced secretion of matrix metalloproteinase-9 through the inactivation of the JNK, p38, and NF-κB pathways in human fibrosarcoma cells

140-GHz subwavelength transmission imaging for foreign body inspection in food products

Photodynamic and photothermal tumor therapy using phase-change material nanoparticles containing chlorin e6 and nanodiamonds

A study on amphiphilic fluorinated block copolymer in graphite exfoliation using supercritical CO2 for stable graphene dispersion

Thermally controllable filter at terahertz region

Free-standing guided-mode resonance humidity sensor in terahertz

Genetic diversity, antimicrobial resistance, toxin gene profiles, and toxin production ability of Bacillus cereus isolates from doenjang, a Korean fermented soybean paste

Facile preparation of gold-coated polydimethylsiloxane particles by in situ reduction without pre-synthesized seed

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