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The extrinsic and intrinsic membrane sectors of F 1 F 0 -ATPases are linked by a slender stalk 40-50 Å in length. The stalk transmits the energy produced by oxidative or photosynthetic phosphorylation from the intrinsic sector, F 0 , to the catalytic sites in the extrinsic F 1 sector. How this is achieved is unknown, but long-range conformational changes linked to transmembrane...
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