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MicroRNA (miRNA) imaging in disease sites is vital to elucidate their role in cancer progression. However, limited tumor specificity remains a major barrier for traditional amplification approaches due to associated background signal leakage. Here, we report a generalizable approach via the combination of enzymatically triggered catalytic hairpin assembly with lipid nanoparticles (LNPs)‐based delivery...
Tumorspezifisches miRNA‐Imaging wird durch die Integration einer durch Enzyme ausgelösten katalytischen Haarnadelverbindung mit Lipid‐Nanopartikeln erreicht. Der Ansatz ermöglicht eine kontrollierte Aktivierung der Signalverstärkung in Krebszellen mit verbessertem Bildgebungskontrast, wie Lele Li, Mengyuan Li et al. in ihrem Forschungsartikel berichten (e202214230).
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