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The present study showed that corticosterone (B) could induce a rapid activation of p38 and c-Jun NH 2 -terminal protein kinase (JNK) in PC12 cells. The dose-response and time-response curves were bell-shaped with maximal activation at 10 -9 M and at 15 min. RU38486 had no effect, and bovine serum albumin-coupled B could induce the activation. Genistein failed to block the phosphorylation,...
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