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Objectives
The aim of this study was to evaluate the applicability of genotyping of the ABCG2 gene using MALDI‐TOF MS and to estimate the allele frequency in the Japanese population.
Background
Jr (a−) phenotype has a prevalence of approximately 0·05% among Japanese blood donors; DNA‐based genotyping was conducted to investigate the molecular basis of the Jr (a−) phenotype along with serological...
BackgroundBlood‐group genotyping arrays have been widely used in Caucasian and African American populations, but have not been thoroughly tested in Japanese subjects.
AimTo evaluate, using the BLOODchip® Reference genotyping system, the concordance of previously typed samples with expected phenotypes and the coverage of the Japanese variants.
MethodsBlood samples from 100 Japanese donors were obtained...
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