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Although secukinumab has demonstrated high efficacy and favorable safety in moderate‐to‐severe psoriasis and psoriatic arthritis, patients developing adverse events of special interest (AESI) were reported increasingly in real‐world practice. A systematic literature search of the PubMed database was conducted to identify clinical studies or case reports on secukinumab‐induced AESI. More than 1077...
Psoriasis is a systemic inflammatory disease commonly associated with postinflammatory hyper‐ and hypo‐pigmentation. Psoriasis‐related cytokines such as IL‐17 and TNF can contribute to these pigmentation changes by regulating both the growth and pigment production of melanocytes. Here, we present the first reported the case of a patient with a 10‐year history of severe psoriasis vulgaris, who developed...
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