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Defects in the Notch pathway ligand Dll3 have been identified in the mouse pudgy (Dll3 pu ) and human spondylocostal dysostosis (SD, MIM 277300) mutations. Although these mutations are primarily associated with segmental defects in the axial skeleton and somitic patterning, they also exhibit cranial neurological defects. Therefore we have looked at the expression of Dll3 in the developing...
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