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The study examined Hypothalamus‐Pituitary‐Adrenal (HPA) axis and inflammatory signaling in 206 youth with histories of prenatal drug exposure and self‐reported histories of maltreatment. Youth with histories of severe neglect showed elevated levels of cortisol, the end product of the HPA axis, in comparison to youth with lower or minimal levels of neglect. Histories of severe neglect also were associated...
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