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Omega-3 polyunsaturated fatty acids (PUFAs) may reduce vulnerability to atrial fibrillation (AF). The mechanism underlying this effect is unknown. A genome wide approach was used to identify gene expression profiles involved in a new model of vulnerability to AF, and determine whether they were altered by PUFA therapy. Thirty-six dogs were randomized into 3 groups of 12. Two groups were paced using...
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