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Background: Studies have shown no correlation between maximum left ventricular wall thickness (LVWT) and survival in patients (pts) with hypertrophic cardiomyopathy (HCM). This may relate to relatively small numbers of pts presenting with LVWT >25-30 mm.Methods: 462 HCM pts (284 male, mean 37 yrs, 1-79) were studied. Pts taking amiodarone or with ICD were excluded. All pts underwent 2D-, and...
Background: We have previously investigated the effect of offsetting and curving the cavae at the TCPC site. Under certain flow conditions, curving the vessels forced flow to turn around large angles with resultant high energy losses. We hypothesize that the introduction of smooth flaring at the site would reduce losses.Methods: Glass models of five flared designs with 0 and 1 SVC diameter offsets...
Background: Patients (pts) with hypertrophic cardiomyopathy (HCM) have reduced peak oxygen uptake (pV 02 ) during upright exercise testing. In patients with cardiovascular disease submaximal parameters are more useful. This study examines the relation of submaximal parameters to clinical symptoms.Methods: 76 consecutive pts (34 F, 44 +/- 15 yrs; 12-74) with HCM underwent metabolic exercise...
Background: Patients (pts) with hypertrophic cardiomyopathy (HCM) are at risk of sudden death. Studies prior to the use of amiodarone or implantable cardioverter defibrillators (ICD) indicate that a third of pts that survive cardiac arrest die over the subsequent five years from ventricular arrhythmia or progressive heart failure.Methods: We studied 16 HCM pts with documented VF or syncopal VT (VT/VF)...
Congestive heart failure (CHF) is not an uncommon presentation in Takayasu arteritis (TA). To understand the pathogenesis of CHF in this disease we carried out endomyocardial biopsy (EMB) in 85 patients (males 29, females 56, age 2 to 42 yrs) with angiographically proven TA. The EMB was done form RV using cordis bioptome and 3 to 5 pieces were taken in 10% formalin for histological examination.Myocardial...
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