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A novel potentiometric immunosensor for the detection of hepatitis B surface antigen has been developed by self-assembling gold nanoparticles to a thiol-containing sol–gel network.A cleaned gold electrode was first immersed in a hydrolyzed (3-mercaptopropyl) trimethoxysilane sol–gel solution to assemble a three-dimensional silica gel, and then gold nanoparticles were absorbed onto the thiol groups...
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