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The introduction of micromachining technologies into design and development of interfaces to the peripheral nervous systems more than 20 years ago led to novel silicon and polymer based microimplants. Polyimide has been chosen as candidate for flexible implants. In this work, the investigations on different designs, the material stability and different aspects of biocompatibility as well as the functional...
Longitudinal intrafascicular electrodes (LIFEs) are electrodes designed to be placed inside the peripheral nerve to improve stimulation selectivity and to increase the recording signal-to-noise ratio. We evaluated the functional and morphological effects of either Pt wire LIFEs or polyimide-based thin-film LIFEs implanted in the rat sciatic nerve for 3 mo. The newly designed thin-film LIFEs are more...
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