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Herpes simplex virus (HSV) infection of the cornea culminates in an immunopathological lesion (stromal keratitis – SK) that impairs vision. This report shows that HSV infection results in IL-23 up-regulation, but if this response fails to occur, as was noted in p19−/− mice, the severity of lesions, their incidence and the level of viral induced angiogenesis were significantly increased compared to...
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