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Stimuli‐responsive ion nanochannels have attracted considerable attention in various fields because of their remote controllability of ionic transportation. For photoresponsive ion nanochannels, however, achieving precise regulation of ion conductivity is still challenging, primarily due to the difficulty of programmable structural changes in confined environments. Moreover, the relationship between...
Infection classification is the key for choosing the proper treatment plans. Early determination of the causative agents is critical for disease control. Host responses analysis can detect variform and sensitive host inflammatory responses to ascertain the presence and type of the infection. However, traditional host‐derived inflammatory indicators are insufficient for clinical infection classification...
Cancer Diagnostics
In article number 2200784, Kun Qian, Jiayi Wang, and co‐workers develop a versatile electrochemical biosensing system for circulating miRNA detection by DNAzyme cleavage cycling amplification and hybridization chain reaction amplification. By profiling miRNA in a non‐small‐cell lung cancer cohort, this designed liquid biopsy strategy shows high efficiency and sensitivity for early...
Circulating microRNAs (miRNAs) can be used as noninvasive biomarkers and are also found circulating in body fluids such as blood. Dysregulated miRNA expression is associated with many diseases, including non‐small cell lung cancer (NSCLC), and the miRNA assay is helpful in cancer diagnosis, prognosis, and monitoring. In this work, a versatile electrochemical biosensing system is developed for miRNA...
Monitoring milk quality is of fundamental importance in food industry, because of the nutritional value and resulting position of milk in daily diet. The detection of small nutrients and toxins in milk is challenging, considering high sample complexity and low analyte abundance. In addition, the slow analysis and tedious sample preparation hinder the large‐scale application of conventional detection...
In article number 1803051, Kun Qian and co‐workers construct a dual‐functional silver platform for the detection and inhibition of bacteria, toward real case applications and biological understandings. The designed platform achieves defined bioanalysis and targeted biotoxicity.
Detection and inhibition of bacteria are universally required in clinics and daily life for health care. Developing a dual‐functional material is challenging and in demand, engaging advanced applications for both defined bioanalysis and targeted biotoxicity. Herein, magnetic silver nanoshells are designed as a multifunctional platform for the detection and inhibition of bacteria. The optimized magnetic...
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