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We hypothesized that combined treatment with cyclooxygenase (Cox)-1 (catechin) and Cox-2 (NS398)–specific inhibitors would reduce cellular proliferation synergistically in genitourinary cancer. Bladder (T24 and TCCSUP) and prostate (DU145, LnCaP, and PC3) cancer cell lines were treated with catechin and NS398 at a dose of 100 μmol/L as single and combined treatments. Viability was measured by MTT...
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