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Abstract. Rationale and objectives: Previous studies have shown that insomniacs self-administer hypnotics at high nightly rates. This study assessed whether insomniacs' self-administration of hypnotics extended to the daytime. Methods: Forty-four healthy men and women, 2155 years old, with (n=22) and without (n=22) insomnia volunteered. They were randomized to one of two triazolam dose groups (0.125...
Objectives: To evaluative whether polysomnographically determined sleep variables in a large group of subjects reflecting a wide range of sleep disturbance would be predictive of the self-administration of capsules before sleep.Methods: Sixty-four healthy men and women with and without insomnia (aged 21-55 years) were given an opportunity to self-administer placebo or triazolam (0.25 mg) capsules...
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