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Wnt signaling pathway significantly participates in cardiac fibrosis and CFs activation. Therefore, we reviewed current evidence on the new perspectives and biological association between Wnt signaling pathway and cardiac fibrosis.A PubMed database search was performed for studies of Wnt signaling pathway in cardiac fibrosis and CFs activation.Numerous studies have shown that the Wnt signaling pathway...
Colorectal cancer is a major health problem worldwide. Aberrant activation of the Wingless-type mouse mammary tumor virus integration site family(Wnt)/β-catenin signaling pathway is the most common and initial alteration in sporadic colorectal tumors. Numerous experimental studies have indicated that β-catenin is a key regulator of colorectal cancer. Indeed, β-catenin activity was shown to designate...
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