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Membrane technology has proven to be a mainstay separation technology over the past two decades. Some major advantages of membrane technology are application without the addition of chemicals and a comparatively low energy use. With its current applications, membrane technology has been widely used in biotechnology processes. Cell harvesting and virus purification/removal are important processes in...
Purification of virus particles and viral vectors for viral vaccines and gene therapy applications is a major large-scale separations challenge. Purification of parvovirus particles such as adeno-associated virus, the leading candidate for gene therapy applications, is particularly challenging given their small size, typically 18–26nm. We have investigated the use of ultrafiltration for purification...
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