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The cornu ammonis 1 (CA1) area in the hippocampus of the parkinsonism‐dementia complex (PDC) of Guam was examined quantitatively with special references to the number of neurons, intraneuronal (i) and extracellular (e) neurofibirillary tangles (NFTs), and TDP‐43 (43‐kDa trans‐activation‐responsive region DNA‐binding protein)‐immunopositive structures, in 24 Chamorro patients with PDC of Guam and seven...
Hippocampal sclerosis is defined as selective neuronal loss and gliosis of the hippocampus with heterogeneous etiologies, including neurodegenerative tauopathies. We report a 78-year-old woman who presented with depression, in whom postmortem examination revealed almost complete loss of neurons with gliosis in the subiculum and CA1-3 regions of the hippocampus and abundant neuronal cytoplasmic inclusions...
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