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Eight days' desipramine administration (16 mg/kg per day i.p.) to rats resulted in a significant decrease in the density of β-adrenoceptors in neuronal and astroglial cells from rat forebrain and cerebellum without modification of their corresponding affinity. β-Adrenoceptor subtypes, β 1 and β 2 , which coexist in neurons and astrocytes, are differently distributed in the brain and...
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