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The central opioid system may have an important influence on memory processes. In view of this, the concentration of β-endorphin-like immunoreactivity (β-ELIR) in cerebrospinal fluid (CSF) was measured by a radioimmunoassay in rats trained in a passive avoidance procedure. The β-ELIR in CSF was examined immediately, 2, 5, 10, and 30 min after the learning trial in which rats were exposed to footshock...
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