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The Columbia Appetitive Seminar, which began in 1972, has been a huge success in bringing together scholars interested in appetitive behavior, stimulating research and new ideas, and encouraging collaborations. At the time of the Seminar’s inception, predominant views were that energy derived acutely from the utilization of glucose was a primary causative factor in determining the initiation (hunger)...
Energy homeostasis is a complex on-going process that includes maintaining immediately available as well as stored nutrient levels at optimal levels given the environment. To accomplish this, the brain receives continuous information about stored energy and current and anticipated fluxes in critical organs, as well as about food that is potentially available or being eaten and absorbed. The brain...
Recent technologic innovations have enabled probing the workings of individual cells and even molecules. As a result, our knowledge of the biological controls over eating and the regulation of body adiposity is increasing at a rapid pace. We review the evidence that food intake is controlled by separate but interacting groups of molecular signals. One group, termed satiety signals, are proportional...
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