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Die Entdeckung der lokalanästhetischen Wirkung durch Blockade der Natriumionenkanäle war ein Meilenstein in der Anästhesie, die jedoch schon bald ihre Limitierung durch z. T. lebensbedrohliche toxische Wirkungen der Lokalanästhetika (LA) erfuhr. Durch Entwicklung neuartiger LA, aber auch durch Hinzunahme sog. Adjuvanzien wurde versucht, diese lebensbedrohlichen Wirkungen einzuschränken. Der vorliegende...
A 39-year-old man was admitted for upper abdominal pain and shortness of breath. The chest roentgenogram demonstrated cardiomegaly and left lower lobe atelectasis. Echocardiography showed circumferential pericardial effusion with signs of cardiac tamponade. Pericardial biopsy and fluid analysis were consistent with fibrino-purulent pericarditis. Despite broad-spectrum antibiotics, percutaneous and...
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