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Acetylserotonin-O-methyltransferase (ASMT) catalyzes the conversion of nor-melatonin to melatonin. Different levels of melatonin have been employed as a trait marker for psychiatric conditions, for this reason ASMT is thought to be an ideal target for developing novel therapeutic agents for the treatment of several mood disorders. In current study, the structural and functional details of the ASMT-B22...
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