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Abstract Discoidin (DS) domains occur in a large variety of proteins. We have recently reported the D1 domain of galactose oxidase (GOase), a copper-containing enzyme whose structure has been determined at 1.7 resolution, as distant member of the DS domain family. The D1 domain of GOase consists of a five-stranded antiparallel -sheet packing against a three-stranded antiparallel -sheet. We here show...
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