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Microtubule dynamics have been shown to contribute to neurite outgrowth, branching, and guidance. Stathmin 1 is a potent microtubule‐destabilizing factor that is involved in the regulation of microtubule dynamics and plays an essential role in neurite elongation and synaptic plasticity. Here, we investigate the expression of stathmin 1 in the brain tissues of patients with intractable temporal lobe...
The gene encoding dystrobrevin‐binding‐protein‐1 (dysbindin) is expressed in many areas of the central nervous system and plays a role in intracellular vesicle trafficking, synaptic vesicle trafficking, and neurotransmitter release. At a cellular level, dysbindin is thought to mediate presynaptic glutamatergic transmission. Using Western blotting and immunofluorescence, we investigated dysbindin expression...
Mical‐1 is a novel F‐actin‐disassembly factor that is critical in actin reorganization. It provides a molecular conduit through which actin reorganizes‐a hallmark of cell morphological changes, including axon navigation. However, whether Mical‐1 is involved in the epileptogenesis remains unknown. Here, we investigate Mical‐1 expression pattern in patients with intractable temporal lobe epilepsy (TLE)...
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