The Infona portal uses cookies, i.e. strings of text saved by a browser on the user's device. The portal can access those files and use them to remember the user's data, such as their chosen settings (screen view, interface language, etc.), or their login data. By using the Infona portal the user accepts automatic saving and using this information for portal operation purposes. More information on the subject can be found in the Privacy Policy and Terms of Service. By closing this window the user confirms that they have read the information on cookie usage, and they accept the privacy policy and the way cookies are used by the portal. You can change the cookie settings in your browser.
Systemic amyloidosis is caused by the misfolding of a circulating amyloid precursor protein and the deposition of amyloid fibrils in multiple organs. Chemical and biophysical analysis of amyloid fibrils from human AL and murine AA amyloidosis reveal the same fibril morphologies in different tissues or organs of one patient or diseased animal. The observed structural similarities concerned the fibril...
N‐terminal verkürzte, Pyroglutamat‐modifizierte Varianten des Aβ‐Peptids sind natürlich vorkommende chemische Modifikationen bei der Alzheimerschen Krankheit. Wir zeigen hier, dass die beiden Modifikationen die Länge der Fibrillen und den Übergangsmittelpunkt der thermischen Entfaltung der Fibrillen signifikant herabsetzen. Die Peptidkonformation in den Fibrillen bleibt jedoch weitestgehend unbeeinflusst...
Set the date range to filter the displayed results. You can set a starting date, ending date or both. You can enter the dates manually or choose them from the calendar.