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This paper demonstrates that polarization microscopy can be a very useful tool for observing the dissolution processes of electrospun drug-loaded nanofiber mats, and thus providing useful information for preparing drug-loaded nanofibers with high quality. With icariin as the model active pharmaceutical ingredient and PVP K30 and K60 as filament-forming matrix, three different types of drug-loaded...
Fast dissolution nanofiber membranes were prepared using electrospinning process with Ferulic Acid (FA)--a traditional Chinese medicine as the active pharmaceutical ingredients and a pharmaceutical hydrophilic polymer--polyvinylpyrrolidone K30 as the filament-forming matrix. Field Emission Scanning Electronic Microscopy (FE-SEM), Differential Scanning Calorimetry (DSC), Attenuated Total Reflection...
With the rapid development of the global industries and the impact this is having on atmospheric and environmental conditions, increased radiations factors are becoming more problematic. This study describes the application of a kind of new green solvent composed of [BMIM] + Cl-) + ([BMIM] + BF4-) ionic liquids by wet spinning to prepare papain-carried wood cellulose fibers. And the dissolution process...
A novel drug delivery device (DDD) with complex structures for providing linear drug release profiles was designed and fabricated directly from the CAD models using three-dimensional printing technique (3DP) systems. The DDDs were in donut shape and had local concentration variations of the release-retarding polymer in their three regions. Environmental scanning electron microscopy clearly showed...
Sustained-release floating drug delivery systems (FDDSs) enable prolonged and continuous input of the drug to the upper parts of the gastrointestinal tract have been designed and fabricated using three dimensional printing (3DP) technology. A new strategy is proposed for the development of FDDSs. The design of FDDSs was based on the sustained release formulation, with low density and floating features...
Fine and continuous composite medicated PAN/PVP fibers were prepared using wet spinning processes. The co-dissolving method was employed to prepare the spinning solution. The prepared fiberts had a diameter of 145 plusmn 17 mum. SEM images showed that the libers had a uniform and homogeneous structure with some nano drug particles aggregated on the fiber surface. X-ray diffraction analysis result...
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