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We profiled nine pure clear cell carcinomas of the breast using massively parallel DNA and RNA sequencing (NGS), in situ hybridization (ISH), and immunohistochemistry (IHC). All cases were primary mammary clear cell carcinomas that were diagnosed in female patients (mean age: 53.4 years; range: 31‐69 years). Based on our findings, we conclude that the majority of clear cell carcinomas are ER/PR positive...
BACKGROUND:Breast Health International and the Kimmel Cancer Center of Thomas Jefferson University cosponsored a consensus conference that included an international group of experts.
METHODS:Since the adoption of adjuvant chemotherapy for stage I, lymph node‐negative breast cancers in 1988, investigators have tried to “fine‐tune” the treatment criteria. At this consensus conference, the group debated...
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