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This work describes the use of layered double hydroxides (LDHs) for the immobilisation of acetylcholinesterase (AChE) on insulator/semiconductor solid supports. Different LDHs have been synthesised by a co-precipitation method. Afterwards, biohybrid materials based on AChE–LDH mixtures have been produced using wild and recombinant enzymes. Spectroscopic techniques have confirmed the LDH phase identity...
This article reviews the recent advances in acetylcholinesterase (AChE) biosensors as screening devices for the detection of samples contaminated wich neurotoxic compounds, with a focus on those dcveloped for carbamate insecticides. The use of AChE enzymes from different organisms or genetically modified to improve the limits of detection and extend the range of detectable compounds is also reviewed...
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