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IgG4‐related disease (IgG4‐RD) is characterized by a lymphoplasmacytic infiltrate composed of IgG4+ plasma cells, tumefactive lesions, obliterative phlebitis, and mild to moderate eosinophilia. It has been suggested that IgG4‐RD is characterized by allergic manifestations and is potentially driven by enhanced T‐helper type 2 (Th2) responses. We aimed to investigate the potential contribution of atopy...
IgG4‐related disease (IgG4‐RD) is a fibroinflammatory disorder that can affect virtually every organ system. T‐helper type 2 responses have been presumed to be pathogenic in this disease, and a high proportion of patients with IgG4‐RD are reported to have longstanding allergies, peripheral blood eosinophilia, and serum IgE elevation. It has therefore been proposed that allergic mechanisms drive IgG4‐RD...
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