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Abstract. In Schwann cells, the transmembrane glycoprotein -dystroglycan composes the dystroglycan complex together with the extracellular glycoprotein -dystroglycan, which binds laminin-2 (2/1/1), a major component of the Schwann cell basal lamina. In the Schwann cell cytoplasm, -dystroglycan is anchored to a dystrophin isoform, Dp116. In this study, we investigated the expression of -dystroglycan,...
Abstract In Schwann cells, the transmembrane glycoprotein -dystroglycan composes the dystroglycan complex, together with the extracellular glycoprotein -dystroglycan which binds laminin-2, a major component of the Schwann cell basal lamina. To provide clues to the biological functions of the interaction of the dystroglycan complex with laminin-2 in peripheral nerve, the expression of -dystroglycan...
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