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Microbe‐produced secondary metabolite phenazine‐1‐carboxylic acid (PCA) facilitates pathogen virulence and defense mechanisms against competitors. Magnaporthe oryzae, a causal agent of the devastating rice blast disease, needs to compete with other phyllosphere microbes and overcome host immunity for successful colonization and infection.
However, whether M. oryzae produces PCA or it has any other...
Pyruvate dehydrogenase kinase 1 (PDK1) is a widely known glycolytic enzyme, and some evidence showed that PDK1 promoted breast cancer by multiple approaches. However, very few lncRNAs have been identified to be associated with PDK1 in breast cancer in previous research. In this study, we found that lncRNA sprouty4‐intron transcript 1 (SPRY4‐IT1) was regulated by PDK1 with correlation analysis, and...
Objective
The aim of this study was to quantify abdominal adiposity and generate data‐driven adiposity subtypes with different diabetes risks.
Methods
A total of 3817 participants from the Pinggu Metabolic Disease Study were recruited. A deep‐learning‐based recognition model on abdominal computed tomography (CT) images (A‐CT model) was developed and validated in 100 randomly selected cases. The...