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Due to a rapid development in biotechnology more and more macromolecular drugs such as therapeutic peptides, oligosaccharides and nucleic acids are entering the pharmaceutical arena representing unprecedented challenges from the drug delivery point of view. One of the likely greatest challenges is their oral administration presenting a series of attractive advantages. Oral Delivery of Macromolecular...
Cinnamaldehyde was covalently bound to the ε-amino group of lysyl residues of lysozyme by reduction with sodium borohydride. This paper describes the enhanced antimicrobial activity against both the Gram negative Escherichia coli and the Gram positive Staphylococcus aureus compared with the activity of lysozyme, cinnamaldehyde or mixtures of both. The minimal inhibition concentration (MIC) of the...
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