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Interactions between selective opioid agonists acting at μ- and δ-opioid receptors were evaluated by co-administering a low-effective dose of the selective μ-opioid receptor agonist ohmefentanyl (OMF) with sequentially increasing doses of the selective δ-opioid receptor agonist [D-Pen 2 , D-Pen 5 ] enkephalin (DPDPE). Microphysiometer was used to measure the extracellular acidification...
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