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During pediatric and neonatal cardiopulmonary bypass (CPB), tiny aortic outflow cannulae (2–3mm inner diameter), with micro-scale blood-wetting features transport relatively large blood volumes (0.3 to 1.0L/min) resulting in high blood flow velocities (2 to 5m/s). These severe flow conditions are likely to complement platelet activation, release pro-inflammatory cytokines, and further result in vascular...
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