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The applied electric field (EF) has shown to have great influence on epileptiform firing. Epilepsy is a dynamical disease charactered by hypersynchronous firing. Taking the electrical characteristic of extracellular medium i.e. ephaptic transmission into consideration, we build a PR model in the presence of the applied electric field. V̄DSout is the DC part of the voltage between soma and dendrite...
Epilepsy is commonly considered to be the result of excessive firing of neurons. This paper investigates firing patterns of single-neuron in the hippocampus CA3 area based on the Pinsky-Rinzel (PR) model and uses closed-loop control with slow variable as the feedback parameter to suppress neuronal firing. Unscented Kalman Filter (UKF) is adopted to estimate the slow variables which contain important...
This paper addresses the problem of simultaneous estimation of the topological structure and unknown parameters of uncertain general complex networks from noisy time series. Usually the complex networks consist of known node models with some unknown parameters and uncertain topological structure. At the same time, only partial states with heavy noise can be observed in real-world complex networks...
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