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This is the first report that suggests that azelastine hydrochloride (AZE) and biscoclaurine alkaloids (CEPH; Cepharanthin®; Kaken Shoyaku, Tokyo, Japan) are useful in the treatment of idiopathic hypereosinophilic syndrome (HES). A 9-year-old boy was referred to our hospital because of fever and a cutaneous eruption. Full blood examination showed a normal hemoglobin level and leukocytosis of 66 400...
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