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Background
The identification of biomarkers correlated with coronavirus disease 2019 (COVID‐19) outcomes is a relevant need for clinical management. Severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) infection is characterized by elevated interleukin (IL)‐6, IL‐10, HLA‐G, and impaired testosterone production.
Objectives
We aimed at defining the combined impact of sex hormones, interleukin‐10,...
Background
Male patients with COVID‐19 have been found with reduced serum total testosterone (tT) levels and with more severe clinical outcomes.
Objectives
To assess total testosterone (tT) levels and the probability of recovering eugonadal tT levels during a minimum 12‐month timespan in a cohort of men who have been followed over time after the recovery from laboratory‐confirmed COVID‐19.
Materials...
Background
Circulating testosterone levels have been found to be reduced in men with severe acute respiratory syndrome coronavirus 2 infection, COVID‐19, with lower levels being associated with more severe clinical outcomes.
Objectives
We aimed to assess total testosterone levels and the prevalence of total testosterone still suggesting for hypogonadism at 7‐month follow‐up in a cohort of 121 men...
Background
Circulating androgens could have a relevant pathobiological role in clinical outcomes in men with severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) infection (COVID‐19).
Objectives
We aimed to assess: (a) circulating sex steroids levels in a cohort of 286 symptomatic men with laboratory‐confirmed COVID‐19 at hospital admission compared to a cohort of 281 healthy men; and (b)...
This work analysed intracellular calcium stores of boar spermatozoa subjected to ‘in vitro’ capacitation (IVC) and subsequent progesterone‐induced acrosome exocytosis (IVAE). Intracellular calcium was analysed through two calcium markers with different physico‐chemical properties, Fluo‐3 and Rhod‐5N. Indicative parameters of IVC and IVAE were also evaluated. Fluo‐3 was located at both the midpiece...
The aim of this work was to determine the existence of a functional Wnt/β‐catenin signaling pathway in boar spermatozoa, which would be linked with the already well‐known GSK‐3 signaling pathway. This was first confirmed by detecting the presence of the specific Frizzled 3 receptor in these cells. Furthermore, this signaling pathway was activated in boar spermatozoa subjected to ‘in vitro’ capacitation...
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