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Hierarchical polymeric carriers with high encapsulation efficiencies are fabricated via a biocompatible strategy developed using superhydrophobic (SH) surfaces. The carries are obtained by the incorporation of cell/BSA‐loaded dextran–methacrylate (DEXT–MA) microparticles into alginate (ALG) macroscopic beads. Engineered devices like these are expected to boost the development of innovative and customizable...
Superhydrophobic surfaces are found by J. F. Mano and co‐workers to constitute a new, versatile, and cost‐effective tool to produce engineered polymeric assemblies in mild conditions. As reported on page 3648, the resultant hierarchical carriers consist of microcarriers embedded in a polymeric matrix and allow the encapsulation of both proteins and cells with high efficiency rates. This work is expected...
5-Fluorouracil (5-FU)-loaded chitosan microgels for oral and topical chemotherapy were prepared applying a superhydrophobic surface-based encapsulation technology. Drug-loaded chitosan dispersions were cross-linked and then coated with drug-free chitosan or pectin layers at the solid-air interface in a highly efficient and environment-friendly way. The size of the microgels (with diameters of ca....
Inspired in nature, the creation of synthetic superhydrophobic surfaces is nowadays a major object of study, with many potential applications in different fields. The fabrication of such substrates has been dominated by the use of non biodegradable and poorly flexible materials, using expensive and complex procedures. To overcome this issue, we propose a simple concept for fabricating low-cost, biodegradable,...
Purpose To implement a bioinspired methodology using superhydrophobic surfaces suitable for producing smart hydrogel beads in which the bioactive substance is introduced in the particles during their formation. Methods Several superhydrophobic surfaces, including polystyrene, aluminum and copper, were prepared. Polymeric solutions composed by photo-crosslinked dextran-methacrylated and thermal...
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