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Dietary concentrations of 0.5% DL-α-methyl phenylalanine (AMPhe), an inhibitor of phenylalanine hydroxylase, plus 3.0% L-phenylalanine (Phe) have been commonly used in a rat model of maternal phenylketonuria (PKU). The treatment causes a marked depression of the food consumption and weight gain of the gestating dam. A study was carried out to determine if lowering the dietary concentrations of AMPhe...
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