Search results for: Yue Fen Wang

Items from 1 to 7 out of 7 results

article

Medicine in Future and Advantages of Integrated Chinese and Western Medicine

Jiang-hua Zhang, Mi-shan Wu, Yue-fen Wang, Ying-min Jia, more

Chinese Journal of Integrative Medicine > 2019 > 25 > 2 > 87-90

The history of medical development shows that oriental medicine, or traditional medicine, was born through medical practice during the times when science and technology were immature and underdeveloped, whereas with the development of science and technology, Western medicine, or modern medicine, was born through experimental analysis and research. With the development of medicine, the pros and cons...

article

Comparative analysis of proteomes between diabetic and normal human sperm: Insights into the effects of diabetes on male reproduction based on the regulation of mitochondria‐related proteins

Tian An, Yue‐Fen Wang, Jia‐Xian Liu, Yan‐Yun Pan, more

Molecular Reproduction and Development > 85 > 1 > 7 - 16

This study sought to identify sources of the reduced fertility of men with type 2 diabetes mellitus. Significant reductions in semen volume, sperm concentration, and total sperm count were observed in diabetic individuals, while transmission electron microscopy revealed that the structure of mitochondria in the tail of sperm from diabetic patients was damaged. Proteins potentially associated with...

article

Sustained release subcutaneous delivery of BMS-686117, a GLP-1 receptor peptide agonist, via a zinc adduct

Feng Qian, Nina Ni, Lori S. Burton, Yue Fen Wang, more

International Journal of Pharmaceutics > 2009 > 374 > 1-2 > 46-52

BMS-686117 is an 11-mer GLP-1 receptor agonist with a short intrinsic pharmacokinetic half-life (t _1/2 ) of ∼2h. In order to develop an extended release formulation for once-daily (QD) subcutaneous administration, a non-covalently bonded Zn/BMS-686117 adduct with very low aqueous solubility was prepared through mixing zinc acetate and BMS-686117 solutions, followed by filtration or spray drying...

article

A simple and sensitive LC/MS/MS assay for 7-ethyl-10-hydroxycamptothecin (SN-38) in mouse plasma and tissues: application to pharmacokinetic study of liposome entrapped SN-38 (LE-SN38)

Sumsullah Khan, Ateeq Ahmad, Wei Guo, Yue-Fen Wang, more

Journal of Pharmaceutical and Biomedical Analysis > 2005 > 37 > 1 > 135-142

An LC/MS/MS method to quantify SN-38 in mouse plasma and tissue homogenates containing liposome entrapped SN-38 (LE-SN38) was developed. Camptothecin (CPT) was used as the internal standard (IS). Sample preparation consisted of simple protein precipitation by acetonitrile containing 0.5% acetic acid. SN-38 and IS were separated by a C18 HPLC column and detected using a mass spectrometer operating...

article

Improved liquid chromatographic method for mitoxantrone quantification in mouse plasma and tissues to study the pharmacokinetics of a liposome entrapped mitoxantrone formulation

Jenifer L. Johnson, Ateeq Ahmad, Sumsullah Khan, Yue-Fen Wang, more

Journal of Chromatography B > 2004 > 799 > 1 > 149-155

A simple, rapid HPLC method for quantification of mitoxantrone in mouse plasma and tissue homogenates in the presence of a liposome entrapped mitoxantrone formulation (LEM-ETU) is described. Sample preparation is achieved by protein precipitation of 100μl plasma or 200μl tissue homogenate with an equal volume of methanol containing 0.5M hydrochloric acid:acetonitrile (90:10, v/v). Ametantrone is used...

article

Exclusion of Chromosome 7 for Kartagener Syndrome but Suggestion of Linkage in Families with Other Forms of Primary Ciliary Dyskinesia

Michal Witt, Yue-fen Wang, Shengbiao Wang, Cui-e Sun, more

The American Journal of Human Genetics > 1999 > 64 > 1 > 313-317

article

Soluble E-selectin in cancer patients as a marker of the therapeutic efficacy of CM101, a tumor-inhibiting anti-neovascularization agent, evaluated in phase I clinical trial

Barbara D. Wamil, Gary B. Thurman, Hakan W. Sundell, Russell F. DeVore, more

Journal of Cancer Research and Clinical Oncology > 1997 > 123 > 3 > 173-179

AbstractA polysaccharide toxin, GBS toxin, is produced by group B Streptococcus (GBS) isolates from neonates who died of early-onset disease. GBS toxin, named CM101 in the clinic, was hypothesized, on the basis of our previous in vivo studies, to induce inflammation in pulmonary neovasculature in neonates by crosslinking of embryonic receptors still expressed after birth and in tumor neovasculature...

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Keywords

PHARMACOKINETICS (2)
ADVANTAGE (1)
ASYMMETRY (1)
CAMPTOTHECIN (1)
CHINESE MEDICINE (1)
CM101 GBS TOXIN CANCER INFLAMMATION NEOVASCULARIZATION ANGIOGENESIS (1)
DIABETES MELLITUS (1)
GLP-1 (1)
IMMOTILE CILIA SYNDROME (1)
INTEGRATED CHINESE AND WESTERN MEDICINE (1)
LC/MS/MS (1)
LIPOSOME (1)
MALE INFERTILITY (1)
MAPPING (1)
MICE (1)
MITOCHONDRIAL METABOLISM (1)
MITOXANTRONE (1)
SITUS INVERSUS (1)
SN-38 (1)
SPERM PROTEOMICS (1)
SPRAY DRYING (1)
SUBCUTANEOUS INJECTION (1)
SUSTAINED RELEASE (1)
THINKING OF MODEL (1)
WESTERN MEDICINE (1)
ZINC (1)
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Elsevier (4)
Springer (2)
Wiley (1)

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Search results for: Yue Fen Wang

Medicine in Future and Advantages of Integrated Chinese and Western Medicine

Comparative analysis of proteomes between diabetic and normal human sperm: Insights into the effects of diabetes on male reproduction based on the regulation of mitochondria‐related proteins

Sustained release subcutaneous delivery of BMS-686117, a GLP-1 receptor peptide agonist, via a zinc adduct

A simple and sensitive LC/MS/MS assay for 7-ethyl-10-hydroxycamptothecin (SN-38) in mouse plasma and tissues: application to pharmacokinetic study of liposome entrapped SN-38 (LE-SN38)

Improved liquid chromatographic method for mitoxantrone quantification in mouse plasma and tissues to study the pharmacokinetics of a liposome entrapped mitoxantrone formulation

Exclusion of Chromosome 7 for Kartagener Syndrome but Suggestion of Linkage in Families with Other Forms of Primary Ciliary Dyskinesia

Soluble E-selectin in cancer patients as a marker of the therapeutic efficacy of CM101, a tumor-inhibiting anti-neovascularization agent, evaluated in phase I clinical trial

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