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Social anxiety disorder (SAD) is the second leading anxiety disorder. On the functional neurobiological level, specific brain regions involved in the processing of anxiety‐laden stimuli and in emotion regulation have been shown to be hyperactive and hyper‐responsive in SAD such as amygdala, insula and orbito‐ and prefrontal cortex. On the level of brain structure, prior studies on anatomical differences...
The aim of this large‐sample cross‐sectional voxel‐based morphometry (VBM) study of anatomical brain data was to investigate linear and nonlinear age‐related trajectories of grey matter volume in the human brain during the adult lifespan. To date, there are only a few structural brain studies investigating local nonlinear aspects at the voxel level, i.e., without using anatomical ROIs as a priori...
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